منابع مشابه
Blue-gray mucocutaneous discoloration: a new adverse effect of ezogabine.
IMPORTANCE Many drugs have been reported to induce skin and/or mucous membrane discoloration. Ezogabine (retigabine) was recently approved as an add-on drug for the treatment of partial seizures in adults with epilepsy. Mucocutaneous discoloration induced by antiepileptic drugs in general and ezogabine in particular has not been previously reported. OBSERVATIONS Two patients who had received ...
متن کاملBlue-gray discoloration of the skin.
Volume 84, Number 7 www.aafp.org/afp American Family Physician 821 A 76-year-old man with a 110-pack-year smoking history and resultant chronic obstructive pulmonary disease presented for a routine primary care appointment. He appeared to have severe hypoxia because of the generalized blue-gray discoloration of his skin and fingernails (Figures 1 and 2). He had no history of heart disease or al...
متن کاملMethylene blue-related corneal edema and iris discoloration.
We report the case of a 70-year-old female patient who developed corneal edema and iris discoloration following the inadvertent use of 1% methylene blue instead of 0.025% trypan blue to stain the anterior capsule during cataract phacoemulsification surgery. Copious irrigation was performed upon realization of incorrect dye use. Corneal edema and iris discoloration developed during the early pos...
متن کاملCharacterizing the discoloration of methylene blue in Fe0/H2O systems.
Methylene blue (MB) was used as a model molecule to characterize the aqueous reactivity of metallic iron in Fe(0)/H(2)O systems. Likely discoloration mechanisms under used experimental conditions are: (i) adsorption onto Fe(0) and Fe(0) corrosion products (CP), (ii) co-precipitation with in situ generated iron CP, (iii) reduction to colorless leukomethylene blue (LMB). MB mineralization (oxidat...
متن کاملPemetrexed long-term maintenance treatment leading to multiple finger amputation; cardiovascular complications after energy drink consumption; compartment syndrome due to extravasation of intravenous contrast; blue-gray mucocutaneous discoloration with ezogabine.
The purpose of this feature is to heighten awareness of specific adverse drug reactions (ADRs), discuss methods of prevention, and promote reporting of ADRs to the US Food and Drug Administration's (FDA's) MedWatch program (800-FDA-1088). If you have reported an interesting, preventable ADR to MedWatch, please consider sharing the account with our readers. Write to Dr. Mancano at ISMP, 200 Lake...
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ژورنال
عنوان ژورنال: JAMA Dermatology
سال: 2014
ISSN: 2168-6068
DOI: 10.1001/jamadermatol.2013.8895